Research Paper Volume 14, Issue 22 pp 9020—9036

Molecular subtypes identified by pyroptosis-related genes are associated with tumor microenvironment cell infiltration in colon cancer


Figure 2. Identification of distinct pyroptosis characterization clusters in colon cancer. (A) Consensus matrices of pyroptosis related genes, for k=3. (B) Principal component analysis for the three clusters based on the pyroptosis gene expression and revealed three entirely disjoint populations in the meta cohort. (C) Survival analyses for the three pyroptosis characterizations including cluster 1, cluster 2 and cluster 3 in the meta cohort. (D) The hierarchical clustering of pyroptosis genes among three pyroptosis characterization clusters. (E) Difference in pyroptosis gene expression between the three clusters.