Research Paper Volume 14, Issue 22 pp 8914—8926

Glutaminase inhibitors rejuvenate human skin via clearance of senescent cells: a study using a mouse/human chimeric model


Figure 5. Effect of senescent cell-depleting agents on SASP expression in aged human skin grafts. Relative mRNA levels of genes associated with SASP in mouse skin measured using qRT-PCR. Data were normalized against mRNA obtained from young human skin; GAPDH was used as endogenous control. All results are expressed as mean ± SEM. *p < 0.05.