Research Paper Volume 14, Issue 24 pp 9890—9907

Sevoflurane-induced POCD-associated exosomes delivered miR-584-5p regulates the growth of human microglia HMC3 cells through targeting BDNF

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Figure 1. Characterization of exosomes isolated from the plasma of sevoflurane-induced post operative cognitive dysfunction (POCD) patients or non-POCD patients. (A) The morphology of exosomes was visualized using a transmission electron microscopy. A NanoSight NS300 particle size analyser was used to analyze the particle size of the exosomes isolated from the plasma of sevoflurane-induced non-POCD patients (B) and POCD patients (C). (D) The expression of exosomes-specific markers TSG101, CD9 and CD81 examined by western blot.