Research Paper Volume 14, Issue 24 pp 10081—10092
SALL4 activates PI3K/AKT signaling pathway through targeting PTEN, thus facilitating migration, invasion and proliferation of hepatocellular carcinoma cells
Figure 3. The effects of SALL4 on the proliferation of hepatic cancers tested by flow cytometry. SALL4 mimic inhibited the cellular ratio in G1 stage and increased the cellular ratio of S stage in both HepG2 (A) and SMMC-7721 cells (B); SALL4 inhibitor suppressed the ratio of G1 stage and increased the ratio of S stage in both HepG2 (A) and SMMC-7721 cells. n = 3/group, t test between two groups, and by one-way analysis of variance among groups. *p < 0.05, **p < 0.01 vs. NC group.