Research Paper Volume 14, Issue 24 pp 10171—10216

The tumor microenvironment in gastrointestinal adenocarcinomas revealed a prognostic and immunotherapeutic biomarker

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Figure 3. TME-C2 subtype was associated with tumor immunity. (A, B) The cancer DNA fraction and Shannon score across three TME subtypes. (C) The expression of current approved and potential immunotherapy targets (PDCD1, CD274, CTLA4, HAVCR2, LAG3 and BTLA) across three TME subtypes. (DH) The immune cell infiltration fraction (leukocyte, CD8 T cell, regulatory T cell, resting NK cell, and activated NK cell) across three TME subtypes.