Research Paper Volume 15, Issue 6 pp 2293—2307

Construction and validation of a hypoxia-related risk signature identified EXO1 as a prognostic biomarker based on 12 genes in lung adenocarcinoma


Figure 2. Expression of genes and function enrichment. (A) Volcano plot and (B) heatmap showing the DEGs between LUAD and normal lung samples. Red dots represent up-regulated and green dots represent down-regulated DEGs, black dots represent no difference, respectively (log FC >1, P < 0.05). (C) GO analysis showing the differentially expressed hypoxia-related genes. (D) The significantly enriched pathways of the DEGs determined by KEGG analysis. Abbreviations: GO: gene ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes.