Research Paper Volume 15, Issue 6 pp 2293—2307

Construction and validation of a hypoxia-related risk signature identified EXO1 as a prognostic biomarker based on 12 genes in lung adenocarcinoma


Figure 3. Ten-fold cross-validation for tuning parameter selection and a gene expression. (A) Plots of the ten-fold cross-validation error rates. (B) LASSO coefficient profiles of the twelve hypoxia-related genes. (C) Relationship between the risk score and clinical significance. (***P-value < 0.001, **P-value < 0.01, and *P-value < 0.05). (D) Associations between the 12 genes. (E) The expression of the 12 genes in different types of tissues.