Renal dysfunction, malignant neoplasms, atherosclerotic cardiovascular diseases, and sarcopenia as key outcomes observed in a three-year follow-up study using the Werner Syndrome Registry

Yukari Maeda; Masaya Koshizaka; Mayumi Shoji; Hiyori Kaneko; Hisaya Kato; Yoshiro Maezawa; Junji Kawashima; Kayo Yoshinaga; Mai Ishikawa; Akiko Sekiguchi; Sei-Ichiro Motegi; Hironori Nakagami; Yoshihiko Yamada; Shinji Tsukamoto; Akira Taniguchi; Ken Sugimoto; Yoichi Takami; Yukiko Shoda; Kunihiko Hashimoto; Toru Yoshimura; Asako Kogure; Daisuke Suzuki; Naoki Okubo; Takashi Yoshida; Kazuhisa Watanabe; Masafumi Kuzuya; Minoru Takemoto; Junko Oshima; Koutaro Yokote

doi:doi:10.18632/aging.204681

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Research Paper Volume 15, Issue 9 pp 3273—3294

Renal dysfunction, malignant neoplasms, atherosclerotic cardiovascular diseases, and sarcopenia as key outcomes observed in a three-year follow-up study using the Werner Syndrome Registry

Figure 2. Percentage of malignant neoplasms onset in each age decile in the patients with Werner syndrome. The blue bar shows the percentage of total malignant neoplasms in each age group. The green bar shows the percentage of epithelial neoplasms in each age group. The red bar shows the percentage of non-epithelial neoplasms in each age group. Patients with thyroid follicular cancer, osteosarcoma, lung cancer/undifferentiated polymorphic sarcoma, and soft tissue sarcoma were excluded because the exact age of onset was unknown.