Research Paper Volume 15, Issue 8 pp 3171—3190

Development and validation of novel prognostic models for zinc finger proteins-related genes in soft tissue sarcoma

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Figure 9. ZNF141 promotes the proliferation and viability of STS cells. (A) ZNF141 expression in normal tissues and STS tissues (GSE2719). The OS (B) and RFS (C) analysis of ZNF141 expression in TCGA cohort. (D) ZNF141 knockdown A673 cells were constructed and confirmed by RT-PCR and Western blotting. (E) The proliferation ability of A673 cells with ZNF141 (si-nc, si-1 or si-2) via CCK8 assays. (F) Plate clone formation assays of A673 cells with ZNF141 (si-nc, si-1 or si-2). (G) ZNF141 overexpression SW982 cells were constructed and confirmed by RT-PCR and Western blotting. (H) The proliferation ability of SW982 cells with ZNF141 overexpression or control plasmid via CCK8 assays. (I) Plate clone formation assays SW982 cells with ZNF141 overexpression or control plasmid.