Featured Nobel Articles

Elizabeth Blackburn, a member of the Editorial Board of Aging, won the Nobel Prize in Physiology or Medicine 2009, while being a member of the board. Elizabeth Blackburn co-authored a paper published in the first (inaugural) issue of Aging.
Andrew V. Schally, Nobel Prize Laureate, published his paper in Aging.
Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging.

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Volume 15, Issue 8

30 April, 2023
pp 2813—3218

About the Cover

The cover features Figure 1 "Oxidative stress-induced wounding results in a chronic wound with increased SA-β-gal expression and SASP burden" from Wyles et al.

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Editorials

Anaphase II processes contribute to aneuploidy in aging oocytes

Anna Kouznetsova,

https://doi.org/10.18632/aging.204640 pp 2813—2814

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Artificial intelligence and the aging mind

Jeyeon Lee, Leland R. Barnard, David T. Jones,

https://doi.org/10.18632/aging.204644 pp 2815—2816

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Mitochondrial redox signaling: a key player in aging and disease

Maria Vitale, Alberto Sanz, Filippo Scialò,

https://doi.org/10.18632/aging.204659 pp 2817—2818

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The senescence-associated secretory phenotype induces neuroendocrine transdifferentiation

Anda Huna, Nadine Martin, David Bernard,

https://doi.org/10.18632/aging.204669 pp 2819—2821

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Neuroimaging and machine learning for brain age estimation

Thomas D. Kocar, Michael Denkinger, Jan Kassubek,

https://doi.org/10.18632/aging.204694 pp 2822—2823

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Research Papers

Single-cell transcriptomic analysis uncovers diverse and dynamic senescent cell populations

Noah Wechter, Martina Rossi, Carlos Anerillas, Dimitrios Tsitsipatis, Yulan Piao, Jinshui Fan, Jennifer L. Martindale, Supriyo De, Krystyna Mazan-Mamczarz, Myriam Gorospe,

https://doi.org/10.18632/aging.204666 pp 2824—2851

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A chronic wound model to investigate skin cellular senescence

Saranya P. Wyles, Parisa Dashti, Tamar Pirtskhalava, Burak Tekin, Christina Inman, Lilian Sales Gomez, Anthony B. Lagnado, Larissa Prata, Diana Jurk, João F. Passos, Tamar Tchkonia, James L. Kirkland,

https://doi.org/10.18632/aging.204667 pp 2852—2862

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Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform

Andrea Olsen, Zachary Harpaz, Christopher Ren, Anastasia Shneyderman, Alexander Veviorskiy, Maria Dralkina, Simon Konnov, Olga Shcheglova, Frank W. Pun, Geoffrey Ho Duen Leung, Hoi Wing Leung, Ivan V. Ozerov, Alex Aliper, Mikhail Korzinkin, Alex Zhavoronkov,

https://doi.org/10.18632/aging.204678 pp 2863—2876

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LINC01296 promotes proliferation of cutaneous malignant melanoma by regulating miR-324-3p/MAPK1 axis

Kang Wang, Qing Luo, Yingfeng Zhang, Xin Xie, Wenhao Cheng, Qiunan Yao, Yingying Chen, Hong Ren, Jiuping Li, Zuanqin Pan,

https://doi.org/10.18632/aging.204413 pp 2877—2890

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Senescence-related genes define prognosis, immune contexture, and pharmacological response in gastric cancer

Xiaogang Shen, Meng Wang, Wenxi Chen, Yu Xu, Qiaoxia Zhou, Tengfei Zhu, Guoqiang Wang, Shangli Cai, Yusheng Han, Chunwei Xu, Wenxian Wang, Lei Meng, Hao Sun,

https://doi.org/10.18632/aging.204524 pp 2891—2905

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Whole-transcriptome sequencing analysis reveal mechanisms of Yiqi Huoxue Yangyin (YHY) decoction in ameliorating D-gal-induced cardiac aging

Xue Wang, Jiaqi Zhang, Chengkui Xiu, Jing Yang, Yiqing Liu, Yan Lei,

https://doi.org/10.18632/aging.204532 pp 2906—2919

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ESM1 promotes angiogenesis in colorectal cancer by activating PI3K/Akt/mTOR pathway, thus accelerating tumor progression

Liqun Yang, Zhigang Dong, Shuyu Li, Tieliang Chen,

https://doi.org/10.18632/aging.204559 pp 2920—2936

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FARSB serves as a novel hypomethylated and immune cell infiltration related prognostic biomarker in hepatocellular carcinoma

Jing Zhen, Jingying Pan, Xuanrui Zhou, Zichuan Yu, Yike Jiang, Yiyang Gong, Yongqi Ding, Yue Liu, Liangyun Guo,

https://doi.org/10.18632/aging.204619 pp 2937—2969

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Ubiquitin-proteasome system-mediated ubiquitination modification patterns and characterization of tumor microenvironment infiltration, stemness and cellular senescence in low-grade glioma

Jun Gu, Lijun Pang, Donghua Yan, Chunming Wang, Yuekun Song, Zhengshuai Jin, Zhenwei Xu, Yuanqing Mao, Shengzhe Liu, Sheng Chen,

https://doi.org/10.18632/aging.204650 pp 2970—2998

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Upregulation of RasGRF1 ameliorates spatial cognitive dysfunction in mice after chronic cerebral hypoperfusion

Li-Jie Yang, Wei Wu, Wan-Rong Jiang, Cheng-Liang Zhu, Zhao-Hui Yao,

https://doi.org/10.18632/aging.204654 pp 2999—3020

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lncRNA TUSC7 sponges miR-10a-5p and inhibits BDNF/ERK pathway to suppress glioma cell proliferation and migration

Runhui Wang, Jia Wang, Yuanyu Wang, Liang Yang,

https://doi.org/10.18632/aging.204655 pp 3021—3034

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TYRO3 promotes tumorigenesis and drug resistance in colorectal cancer by enhancing the epithelial-mesenchymal transition process

Xinyu Shao, Yibin Sun, Kaiqiang Zhong, Jinrong Gu, Yang Yu, Tong Hu, Xiaoyi Kuai, Yechen Xing,

https://doi.org/10.18632/aging.204656 pp 3035—3051

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Association between red blood cell distribution width and ischemic stroke recurrence in patients with acute ischemic stroke: a 10-years retrospective cohort analysis

Zhan Shen, Ying Huang, Ying Zhou, Jingying Jia, Xian Zhang, Tingting Shen, Shengjie Li, Siyang Wang, Yunxiao Song, Jie Cheng,

https://doi.org/10.18632/aging.204657 pp 3052—3063

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Cellular senescence-related gene signature as a valuable predictor of prognosis in hepatocellular carcinoma

Shuqiao Zhang, Yilu Zheng, Xinyu Li, Shijun Zhang, Hao Hu, Weihong Kuang,

https://doi.org/10.18632/aging.204658 pp 3064—3093

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Identification of the pyroptosis-related gene signature and risk score model for esophageal squamous cell carcinoma

Minghong Pan, Yuanyong Wang, Zhaoyang Wang, Changjian Shao, Yingtong Feng, Peng Ding, Hongtao Duan, Xiaoya Ren, Weixun Duan, Zhiqiang Ma, Xiaolong Yan,

https://doi.org/10.18632/aging.204661 pp 3094—3106

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Melatonin induces cell cycle arrest and suppresses tumor invasion in urinary bladder urothelial carcinoma

Tzuo-Yi Hsieh, Wen-Wei Sung, Ya-Chuan Chang, Chia-Ying Yu, Li-Yu Lu, Chen Dong, Tsung-Hsien Lee, Sung-Lang Chen,

https://doi.org/10.18632/aging.204673 pp 3107—3119

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An artificial neural network model to diagnose non-obstructive azoospermia based on RNA-binding protein-related genes

Fan Peng, Bahaerguli Muhuitijiang, Jiawei Zhou, Haoyu Liang, Yu Zhang, Ranran Zhou,

https://doi.org/10.18632/aging.204674 pp 3120—3140

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Profiling and integrated analysis of transcriptional addiction gene expression and prognostic value in hepatocellular carcinoma

Xiaowei Du, Hao Wang, Jing Xu, Yufei Zhang, Tingsong Chen, Gao Li,

https://doi.org/10.18632/aging.204676 pp 3141—3157

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Association of survival with adjuvant radiotherapy for pN0 esophageal cancer

Huijiang Gao, Yuanyong Wang, Zhihui Jiang, Guodong Shi, Shiyu Hu, Jiangshan Ai, Zhaofeng Wang, Yucheng Wei,

https://doi.org/10.18632/aging.204677 pp 3158—3170

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Development and validation of novel prognostic models for zinc finger proteins-related genes in soft tissue sarcoma

Junqing Li, Quan Zhou, Changsheng Zhang, Huimin Zhu, Jie Yao, Meng Zhang,

https://doi.org/10.18632/aging.204682 pp 3171—3190

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Review

How can we modulate aging through nutrition and physical exercise? An epigenetic approach

Ana Teresa Rajado, Nádia Silva, Filipa Esteves, David Brito, Alexandra Binnie, Inês M. Araújo, Clévio Nóbrega, José Bragança, Pedro Castelo-Branco, ALFA Score Consortium,

https://doi.org/10.18632/aging.204668 pp 3191—3217

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Correction

Correction for: Comprehensive analysis of prognostic value, relationship to cell cycle, immune infiltration and m6A modification of ZSCAN20 in hepatocellular carcinoma

Fang Jiayu, Yike Jiang, Xuanrui Zhou, Minqin Zhou, Jingying Pan, Yun Ke, Jing Zhen, Da Huang, Weifan Jiang,

https://doi.org/10.18632/aging.204699 pp 3218

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