Research Paper Volume 15, Issue 11 pp 4746—4756

Calcium silicate-stimulated adipose-derived stem cells promote angiogenesis and improve skin wound healing


Figure 6. CS-stimulated ADSCs improve wound healing in full-thickness skin defect mouse model. (AC) A full-thickness skin defect mouse model was constructed, and the mice were treated with ADSCs, ADSCs and HUVEC, or co-treated with ADSCs, HUVEC, and CaSiO3. (A) The representative images of wound area were shown. (B) The levels of CD31 were measured by immunohistochemistry. (C) The collagen deposition was analyzed by Masson’s trichrome staining.