Research Paper Volume 15, Issue 11 pp 4757—4773

Knocking down NSUN5 inhibits the development of clear cell renal cell carcinoma by inhibiting the p53 pathway

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Figure 6. Knockdown of NSUN5 inhibited ccRCC cell proliferation and promoting ccRCC cell apoptosis. (A, B) Verification of knockdown efficiency of NSUN5 from mRNA level and protein level. (C) A CCK-8 assay was used to detect the effect of NSUN5 on the proliferation of ccRCC cells. (D) After knockdown of NSUN5, cell apoptosis in each group was detected by flow cytometry (*P < 0.05, **P < 0.01, ****P < 0.0001).