Research Paper Volume 15, Issue 18 pp 9250—9274

High-throughput single-cell profiling of B cell responses following inactivated influenza vaccination in young and older adults


Figure 6. The largest persistent clone in the oldest subject O3. (A) The cells from the large persistent clone from the oldest subject are highlighted on the gene expression UMAP plot. The color indicates the cell type. The clone consists of only IgG cells. (B) Mutation frequency in the heavy chain V-segment of the cells within the clone between days was visualized in the box plot. No significant difference between days was observed by the Wilcoxon rank-sum test.