Research Paper Volume 15, Issue 11 pp 4667—4684

Identification of novel genes associated with exercise and calorie restriction effects in skeletal muscle


Figure 5. Selected genes regulate mitochondrial respiration and β-oxidation-associated gene expression. (AG) mRNA expression of mitochondrial respiration-related genes (Ndufs1, Ndufs2, Ndufs8, Sdh, Atp5b, Tfam, and Ppargc1a) and β-oxidation-related genes (Acadm, Acca2, Acsl1, and Acox1) measured by qPCR in C2C12 myotubes with knockdown of selected genes (n = 3). All data are represented as mean ± SEM. Statistically significant differences are denoted as *p < 0.05, **p < 0.01, ***p < 0.005.