Research Paper Volume 15, Issue 18 pp 9377—9390
Ar-turmerone inhibits the proliferation and mobility of glioma by downregulating cathepsin B
Figure 5. Overexpressing CTSB prevented G1/S−phase cell cycle arrest in ar-turmerone−treated glioma cells. Glioma cells were treated with DMSO, ar-turmerone, CTSB plasmids or ar-turmerone + CTSB plasmids, respectively. (A) Western blotting was used to detect the expression of CTSB, P27, CDK2 and CyclinD1 in each group of cells. (B) Flow cytometry was performed to detect the cell cycle distribution of glioma cells in each group. *P < 0.05.