Research Paper Volume 15, Issue 18 pp 9479—9498

Complement and coagulation cascades pathway-related signature as a predictor of immunotherapy in metastatic urothelial cancer


Figure 1. Identification and enrichment analysis of DEGs. (A) DEGs between responders (CR or PR) and non-responders (SD or PD) groups. (B) KEGG pathway enrichment analysis of the 1613 DEGs. (C) KEGG pathway enrichment analysis of the increased and decreased genes in responders. (D) Comparison of complement and coagulation cascades pathway score generated by ssGSEA between responders and non-responders. DEGs, differentially expressed genes; KEGG, Kyoto Encyclopedia of Genes and Genomes; CR, complete response; PR, partial response SD, stable disease; PD, progressive disease; ssGSEA, single sample gene set enrichment analysis.