Research Paper Volume 15, Issue 19 pp 10072—10088

Exploring anti-acute kidney injury mechanism of Dahuang-Gancao decoction by network pharmacology and experimental validation


Figure 8. Expression of the SIRT3/NRF2/HO-1 signaling pathway. (A) Representative images of the effect of DHGC on the SIRT3/NRF2/HO-1 signaling pathway in AKI mice by Western blot. (B) Statistical analysis of the results of the Western blot. (C) Expression of SIRT3, NRF2, and HO-1 in kidney tissues at mRNA level. Data are presented as the mean ± SD. **P < 0.01 vs. Ctrl group; #P < 0.05, ##P < 0.01 vs. AKI group.