Research Paper Volume 15, Issue 18 pp 9544—9560

Human umbilical cord mesenchymal stem cells-derived exosomes exert anti-inflammatory effects on osteoarthritis chondrocytes


Figure 3. The anti-inflammatory effect of hUC-MSCs-Exos was evaluated chondrocytes inflammation model. (A) The expressions of COL2A1 and MMP13 mRNA of chondrocytes were assayed by qRT-PCR. This experiment was repeated three times. **P < 0.01, ***P < 0.001. (B) Immunofluorescence staining was used to detect the protein expression of COL2A1 and MMP13 (green) in chondrocytes. Hoechst 33342 (blue) is utilized to stain the nucleus of chondrocytes. Scale bar=50 μm.