Integrated single-cell and bulk RNA sequencing revealed the molecular characteristics and prognostic roles of neutrophils in pancreatic cancer

Biao Zhang; Jiaao Sun; Hewen Guan; Hui Guo; Bingqian Huang; Xu Chen; Feng Chen; Qihang Yuan

doi:doi:10.18632/aging.205044

← Back

Research Paper Volume 15, Issue 18 pp 9718—9742

Integrated single-cell and bulk RNA sequencing revealed the molecular characteristics and prognostic roles of neutrophils in pancreatic cancer

Figure 5. Correlation between neutrophil-related genes (NRGs) cluster subtypes and drug sensitivity. Increased sensitivity of NRGcluster B to 5-fluorouracil (A), cisplatin (B), KRAS (G12C) inhibitor-12 (C), gemcitabine (D), irinotecan (E), oxaliplatin (F), and paclitaxel (G), increased sensitivity of NRGcluster A to selumetinib (H) and trametinib (I).