Research Paper Volume 15, Issue 18 pp 9718—9742

Integrated single-cell and bulk RNA sequencing revealed the molecular characteristics and prognostic roles of neutrophils in pancreatic cancer

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Figure 9. Analysis of metabolic pathways and immune infiltration using the prognostic models. (A) Gene set variation analysis (GSVA) results. (B) Gene set enrichment (GSEA) results. (C) Single-sample GSEA (ssGSEA) results. Risk scores were significantly and positively correlated with neutrophil infiltration levels (D), significantly and negatively correlated with CD8+ T cell infiltration levels (E), significantly and negatively correlated with naïve B cell infiltration levels (F), significantly and positively correlated with M0 macrophage infiltration levels (G), significantly and negatively correlated with monocyte infiltration levels (H), significantly and positively correlated with activated dendritic cell infiltration levels (I), and significantly and positively correlated with resting dendritic cell infiltration levels (J).