Research Paper Volume 15, Issue 18 pp 9809—9821

The oncogenic miR-429 promotes triple-negative breast cancer progression by degrading DLC1

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Figure 2. The proliferation, migration, and invasion of TNBC cell were promoted by miR-429. (A) qRT-PCR analysis of miR-429 expression in TNBC cell transfected with miR-429 mimic, mimic NC, miR-429 Inhibitor or Inhibitor NC; The cell growth curves of (B) mimic NC, miR-429 mimic, miR-429 Inhibitor and Inhibitor NC groups were evaluated by CCK8 assays; Wound healing assays in (C) mimic NC and miR-429 mimic groups and (D) Inhibitor NC and miR-429 Inhibitor groups were executed to detect the cell migration of transfection groups (magnification, × 100). Transwell assays in (E) mimic NC and miR-429 mimic groups and (F) Inhibitor NC and miR-429 Inhibitor groups were executed to detect the cell invasion of transfection groups (magnification, × 200). All figures are at a scale of 50μm. (* p < 0.05, ** p < 0.01, and *** p < 0.001).