Research Paper Volume 15, Issue 20 pp 10875—10896
Tissue immunoexpression of IL-6 and IL-18 in aging men with BPH and MetS and their relationship with lipid parameters and gut microbiota-derived short chain fatty acids
Figure 4. Increase in cytoplasmic immunoexpression of IL-6 and IL-18 in prostate tissue with benign hyperplasia in MetS patients. (A) IL-6 expression levels significantly increased in prostate stromal cells of BPH + MetS patients. (B) No significant changes in IL-6 immunoexpression were observed in prostate epithelial cells, regardless of group. (C) No significant changes in IL-18 immunoexpression were also observed in the prostate stroma (D), while in the case of glandular epithelial cells, an increase in the percentage of IL-18 positive cells was observed in the BPH + MetS group.