Research Paper Volume 15, Issue 19 pp 10580—10592

Impact of alternating amino acid sequences on beta-amyloid-induced neurotoxicity and neuroinflammation in Alzheimer's disease


Figure 2. (A) The expression of interferon-γ (IFNγ), IL-6, interleukin-1β (IL-1β) and tumor necrosis factorα (TNFα) in the hippocampus and cortex in 3-month-old 5XFAD and wild-type mice (n = 4~8), (B) The expression of IFN-γ and IL-1β in 6-month-old 5XFAD and wild-type mice (n = 7~8), (C) The expression of inflammatory cytokines (IL-2, IL-13, IL-10, TNFα, IL-1b, IL-6, MCP-1, IL-17A, IL-1a) in the serum of 8-month-old 5XFAD and wild-type mice (n = 3) (*P < 0.05, **P < 0.01, ***P < 0.001).