Priority Research Paper Volume 15, Issue 20 pp 10821—10855

Figure 4. ECM-enrichment maintains collagen I and III. (A, C) Representative images of PSR stained ovarian tissue sections from reproductively young and old mice following treatment with 0.1% SDS for 0 h (A, Native) or 12.5 h (C, ECM-enriched). Bottom row of each panel is optical zoom of boxed region from top row. Scale bar for top row for each panel = 400 μm. Scale bar for bottom row for each panel = 100 μm. (B, D) Quantification of fold-change of relative PSR-positive ovarian area in native (B) and ECM-enriched (D) ovaries from reproductively old mice over young counterparts. N = 6 ovaries per group.