Research Paper Volume 16, Issue 1 pp 431—444
TBC1D1 represses glioma progression by altering the integrity of the cytoskeleton
Figure 5. Knockdown TBC1D1 inhibits glioma cell migration and invasion. (A) Detection of migration and invasion of transfected cells by transwell method (Scale bar = 100 μm). (B) Detection of E-cadherin, N-cadherin, MMP-2 and MMP-9 protein expression. (C) Perform wound-healing assay to detect migration of transfected cells (Scale bar = 200 μm). (All data were presented as mean ± s.d. from three independent experiments (*P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001).