Research Paper Volume 16, Issue 2 pp 1696—1711

Therapeutic strategies and predictive models for Xp11.2 translocation/TFE3 gene fusion renal cell carcinoma in adults based on data of two Chinese medical centers


Figure 5. Representative images of TFE3 immunohistochemical staining and microscopic appearance for Xp11.2 RCC. (A) Blood sinusoid and Psammoma bodies were abundant in intercellular substance. The arrow points to Psammoma bodies; (B) abundant and deeply stained eosinophile cytoplasm, similar to renal clear cell carcinoma; (C) the results of immunohistochemistry showed that TFE3 was strongly positive in cancerous tissue; (D) FISH test results: 100 cells were counted, and the number of cells with TFE3 gene breakage was more than 20. TFE3 gene probe: Broken (positive).