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The cover features Figure 6 "Immunotherapy response prediction of senescence related TME risk model and STCGs expression in single cell level" from Lee et al.

Volume 16, Issue 2

31 January, 2024
pp 985—1982

About the Cover

The cover features Figure 6 "Immunotherapy response prediction of senescence related TME risk model and STCGs expression in single cell level" from Lee et al.


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Research Papers

Prognostic significance of senescence-related tumor microenvironment genes in head and neck squamous cell carcinoma

Young Chan Lee, Yonghyun Nam, Minjeong Kim, Su Il Kim, Jung-Woo Lee, Young-Gyu Eun, Dokyoon Kim,
https://doi.org/10.18632/aging.205346 pp 985—1001
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Epigenetic drift underlies epigenetic clock signals, but displays distinct responses to lifespan interventions, development, and cellular dedifferentiation

Emily M. Bertucci-Richter, Ethan P. Shealy, Benjamin B. Parrott,
https://doi.org/10.18632/aging.205503 pp 1002—1020
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Potential prognosis and immunotherapy predictor TFAP2A in pan-cancer

Chenxi Niu, Haixuan Wen, Shutong Wang, Guang Shu, Maonan Wang, Hanxi Yi, Ke Guo, Qiong Pan, Gang Yin,
https://doi.org/10.18632/aging.205225 pp 1021—1048
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Prediction significance of autophagy-related genes in survival probability and drug resistance in diffuse large B-cell lymphoma

Dan Xiong, Xiaolei Wei, Weiming Huang, Jingxia Zheng, Ru Feng,
https://doi.org/10.18632/aging.205282 pp 1049—1076
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Establishing the role of BRCA1 in the diagnosis, prognosis and immune infiltrates of breast invasive cancer by bioinformatics analysis and experimental validation

Leilei Li, Shuangyan Li, Xuyang Zhang, Liying Mei, Xueqin Fu, Min Dai, Na Wei,
https://doi.org/10.18632/aging.205366 pp 1077—1095
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TRPV1 modulated NLRP3 inflammasome activation via calcium in experimental subarachnoid hemorrhage

Keke Zhang, Zhen Qin, Jinyan Chen, Gengyin Guo, Xiaokun Jiang, Feng Wang, Jianfeng Zhuang, Zhen Zhang,
https://doi.org/10.18632/aging.205379 pp 1096—1110
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AMIGO2 is a pivotal therapeutic target related to M2 polarization of macrophages in pancreatic ductal adenocarcinoma

Shensi Chen, Wujun Du, Ke Feng, Ke Liu, Cunji Li, Shengming Li, Hua Yin,
https://doi.org/10.18632/aging.205380 pp 1111—1127
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An enriched environment ameliorates maternal sleep deprivation-induced cognitive impairment in aged mice by improving mitochondrial function via the Sirt1/PGC-1α pathway

Ru-Meng Wei, Yue-Ming Zhang, Kai-Xuan Zhang, Gao-Xia Liu, Xue-Yan Li, Jing-Ya Zhang, Wei-Zhong Lun, Xue-Chun Liu, Gui-Hai Chen,
https://doi.org/10.18632/aging.205385 pp 1128—1144
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Sesamin-mediated high expression of BECN2 ameliorates cartilage endplate degeneration by reducing autophagy and inflammation

Baining Zhang, Zhiwei He, Jialin Guo, Feng Li, Zhi Huang, Wenkai Zheng, Wenhua Xing, Manglai Li, Yong Zhu, Xuejun Yang,
https://doi.org/10.18632/aging.205386 pp 1145—1160
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A circRNA ceRNA network involved in cognitive dysfunction after chronic cerebral hypoperfusion

Wan-Rong Jiang, Yong-Ming Zhou, Wei Wu, Li-Jie Yang, You Wu, Xin-Yuan Zhang, Zhao-Hui Yao,
https://doi.org/10.18632/aging.205387 pp 1161—1181
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Myeloid-specific knockout of Notch-1 inhibits MyD88- and TRIF-mediated TLR signaling pathways by regulating oxidative stress-SHP2 axis, thus restraining aneurysm progression

Yu Li, Ailin Guo, Jianlei Liu, Lijuan Tang, Lide Su, Zonghong Liu,
https://doi.org/10.18632/aging.205392 pp 1182—1191
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Gut microbial community and fecal metabolomic signatures in different types of osteoporosis animal models

Xiaochen Qiao, Xiaoyan Li, Zhichao Wang, Yi Feng, Xiaochun Wei, Lu Li, Yongchun Pan, Kun Zhang, Ruhao Zhou, Lei Yan, Pengcui Li, Chaojian Xu, Zhi Lv, Zhi Tian,
https://doi.org/10.18632/aging.205396 pp 1192—1217
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Development and validation of a combined cuproptosis and immunogenic cell death prognostic model for diffuse large B-cell lymphoma

Nana Wang, Shanshan Shi, Moran Li, Xiaoning Yu, Guangxin Ma,
https://doi.org/10.18632/aging.205399 pp 1218—1236
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Silencing of METTL3 prevents the proliferation, migration, epithelial-mesenchymal transition, and renal fibrosis of high glucose-induced HK2 cells by mediating WISP1 in m6A-dependent manner

Yuanzhen Chen, Ping Li, Mei Lin, Ying Jiang, Guiping Tan, Lianfang Huang, Dan Song,
https://doi.org/10.18632/aging.205401 pp 1237—1248
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Disulfidptosis status influences prognosis and therapeutic response in clear cell renal cell carcinoma

Weiming Deng, Zhenwei Xie, Libo Chen, Wenjin Li, Mingyong Li,
https://doi.org/10.18632/aging.205405 pp 1249—1275
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Molecular subgroup establishment and signature creation of lncRNAs associated with acetylation in lung adenocarcinoma

Hao Chen, Yuanyong Wang, Changjian Shao, Kai Guo, Guanglin Liu, Zhaoyang Wang, Hongtao Duan, Minghong Pan, Peng Ding, Yimeng Zhang, Jing Han, Xiaolong Yan,
https://doi.org/10.18632/aging.205407 pp 1276—1297
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α-Hederin promotes ferroptosis and reverses cisplatin chemoresistance in non-small cell lung cancer

Shugao Han, Xi Yang, Jing Zhuang, Qing Zhou, Jingjing Wang, Lixin Ru, Furong Niu, Wei Mao,
https://doi.org/10.18632/aging.205408 pp 1298—1317
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Long non-coding RNA MEG3 acts as a suppressor in breast cancer by regulating miR-330/CNN1

Dandan Yi, Zetian Wang, Haojie Yang, Ru Wang, Xianbiao Shi, Zhijian Liu, Fazhan Xu, Qing Lu, Xiao Chu, Jianfeng Sang,
https://doi.org/10.18632/aging.205419 pp 1318—1335
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Cisplatin and doxorubicin chemotherapy alters gut microbiota in a murine osteosarcoma model

Zhi Tian, Xiaochen Qiao, Zhichao Wang, Xiaoyan Li, Yongchun Pan, Xiaochun Wei, Zhi Lv, Pengcui Li, Qiujing Du, Wenhao Wei, Lei Yan, Song Chen, Chaojian Xu, Yi Feng, Ruhao Zhou,
https://doi.org/10.18632/aging.205428 pp 1336—1351
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MicroRNA-141-3p reduces pulmonary hypoxia/reoxygenation injury through suppression of Beclin-1-dependent autophagy

Yanping Zhan, Lei Li, Chen Guo, Yang Zhang, Lili Zhao, Zhe Tao, Hua Zhang, Shibiao Chen,
https://doi.org/10.18632/aging.205430 pp 1352—1373
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Treadmill exercise can regulate the redox balance in the livers of APP/PS1 mice and reduce LPS accumulation in their brains through the gut-liver-kupffer cell axis

Shunling Yuan, Yirong Wang, Jialun Yang, Yingzhe Tang, Weijia Wu, Xiangyuan Meng, Ye Jian, Yong Lei, Yang Liu, Changfa Tang, Zhe Zhao, Fei Zhao, Wenfeng Liu,
https://doi.org/10.18632/aging.205432 pp 1374—1389
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Ganodermanontriol regulates tumor-associated M2 macrophage polarization in gastric cancer

Likang Zhang, Pinghui Shi, Peng Jin, Zhenwei Chen, Biwen Hu, Chenxi Cao, Xiaoguang Wang, Jian Sheng,
https://doi.org/10.18632/aging.205434 pp 1390—1398
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Identification of CD8+ T cell-related biomarkers and immune infiltration characteristic of rheumatoid arthritis

Qizun Wang, Qianqian Li, Ronghuan Wang, Yanning Li, Jie Wang, Zhu Guo, Feng Li, Bohua Chen, Hongfei Xiang, Tianrui Wang, Xiaolin Wu,
https://doi.org/10.18632/aging.205435 pp 1399—1413
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Combination of bulk RNA sequencing and scRNA sequencing uncover the molecular characteristics of MAPK signaling in kidney renal clear cell carcinoma

Xiunan Li, Hewen Guan, Chuanyu Ma, Yunfei Dai, Ji Su, Xu Chen, Qihang Yuan, Jianbo Wang,
https://doi.org/10.18632/aging.205436 pp 1414—1439
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Identification and validation of SLCO4C1 as a biological marker in hepatocellular carcinoma based on anoikis classification features

Tianbing Wang, Kai Guo, Shoushan Yang, Di Zhang, Haodong Cui, Jimin Yin, Shuhui Yuan, Yong Wang, Yong Qi, Wenyong Wu,
https://doi.org/10.18632/aging.205438 pp 1440—1462
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Identification and validation of anoikis-related lncRNAs for prognostic significance and immune microenvironment characterization in ovarian cancer

Lixue Cao, Shaofen Zhang, Haojie Peng, Yongqing Lin, Zhihui Xi, Wumei Lin, Jialing Guo, Geyan Wu, Fei Yu, Hui Zhang, Haiyan Ye,
https://doi.org/10.18632/aging.205439 pp 1463—1483
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LRP6 is a potential biomarker of kidney clear cell carcinoma related to prognosis and immune infiltration

Liqun Lu, Yan Lei, Yanling Li, Lujuan Wang,
https://doi.org/10.18632/aging.205440 pp 1484—1495
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The miR-146b-3p/TNFAIP2 axis regulates cell differentiation in acute myeloid leukaemia

Gaochen Lan, Xiaolong Wu, Aiyue Zhao, Jinjian Lan, Qiusheng Guo, Bolin Wang, Fenglin Shen, Xiaoling Yu, Yanna Zhao, Ruilan Gao, Tianwen Xu,
https://doi.org/10.18632/aging.205441 pp 1496—1515
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Molecular map of cGAS-STING pathway-related genes in bladder cancer: the perspective toward immune microenvironment and prognosis

Dong Wei, Ying Liu, Ying Yuan, Yishuai Li, Fangchao Zhao, Xuebo Qin,
https://doi.org/10.18632/aging.205442 pp 1516—1535
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Prognostic characteristics of a six-gene signature based on ssGSEA in sarcoma

Jun Liu, Jianjun Lu, Gefei Wang, Liming Gu, Wenli Li,
https://doi.org/10.18632/aging.205443 pp 1536—1554
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Joint analysis of proteome, transcriptome, and multi-trait analysis to identify novel Parkinson’s disease risk genes

Jing-Jing Shi, Cheng-Yuan Mao, Ya-Zhou Guo, Yu Fan, Xiao-Yan Hao, Shuang-Jie Li, Jie Tian, Zheng-Wei Hu, Meng-Jie Li, Jia-Di Li, Dong-Rui Ma, Meng-Nan Guo, Chun-Yan Zuo, Yuan-Yuan Liang, Yu-Ming Xu, Jian Yang, Chang-He Shi,
https://doi.org/10.18632/aging.205444 pp 1555—1580
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Identification of a basement membrane gene signature for predicting prognosis and estimating the tumor immune microenvironment in prostate cancer

Tao Xie, Du-Jiang Fu, Kang-Jing Li, Jia-Ding Guo, Zhao-Ming Xiao, Zhijie Li, Shan-Chao Zhao,
https://doi.org/10.18632/aging.205445 pp 1581—1604
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SLC7A8 overexpression inhibits the growth and metastasis of lung adenocarcinoma and is correlated with a dismal prognosis

Fang-Ming Wang, Li-Qiang Xu, Zhong-Chao Zhang, Qiang Guo, Zhi-Peng Du, Yue Lei, Xu Han, Chuang-Yan Wu, Feng Zhao, Jiu-Ling Chen,
https://doi.org/10.18632/aging.205446 pp 1605—1619
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PROX1 interaction with α-SMA-rich cancer-associated fibroblasts facilitates colorectal cancer progression and correlates with poor clinical outcomes and therapeutic resistance

Shiue-Wei Lai, Yi-Chiao Cheng, Kee-Thai Kiu, Min-Hsuan Yen, Ying-Wei Chen, Vijesh Kumar Yadav, Chi-Tai Yeh, Kuang-Tai Kuo, Tung-Cheng Chang,
https://doi.org/10.18632/aging.205447 pp 1620—1639
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FABP6 serves as a new therapeutic target in esophageal tumor

Dengfeng Zhang, Fangchao Zhao, Haitao Liu, Pengfei Guo, Zhirong Li, Shujun Li,
https://doi.org/10.18632/aging.205448 pp 1640—1662
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Usenamine A triggers NLRP3/caspase-1/GSDMD-mediated pyroptosis in lung adenocarcinoma by targeting the DDX3X/SQSTM1 axis

Min Li, Rongrong Wu, Le Wang, Dongyi Zhu, Shinan Liu, Ruolan Wang, Chaowen Deng, Shenglin Zhang, Min Chen, Ruojin Lu, Hongxing Zhu, Mengting Mo, Xiaoqiong He, Zhuang Luo,
https://doi.org/10.18632/aging.205450 pp 1663—1684
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Trends in suicide mortality among cancer survivors in the US, 1975-2020

Hao Wan, Ru Chen, Xiangpeng Zhan, Luyao Chen, Zhongyuan Li,
https://doi.org/10.18632/aging.205451 pp 1685—1695
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Therapeutic strategies and predictive models for Xp11.2 translocation/TFE3 gene fusion renal cell carcinoma in adults based on data of two Chinese medical centers

Yunkai Yang, Changfeng Zhao, Zhida Wang, Feng Liu, Ming Zhao, Huiwen Yang, Jun Chen, Xuejing Chen, Min Shi, Dixing Jiang, Xiaoting Luo, Yue Duan, Yuchen Bai,
https://doi.org/10.18632/aging.205452 pp 1696—1711
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Malignant cell receptor-ligand subtypes guide the prediction of prognosis and personalized immunotherapy of liver cancer

Junzheng Wu, Chuncheng Wu, Xianhui Cai, Peipei Li, Jianjun Lin, Fuqiang Wang,
https://doi.org/10.18632/aging.205453 pp 1712—1732
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Identification and validation of methylation-CpG prognostic signature for prognosis of hepatocellular carcinoma

Chunmei He, Zehao Guo, Hao Zhang, Ganqing Yang, Jintao Gao, Zhijing Mo,
https://doi.org/10.18632/aging.205454 pp 1733—1749
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Development and validation of glycosyltransferase related-gene for the diagnosis and prognosis of head and neck squamous cell carcinoma

Miao He, Li Wang, Zihan Yue, Chunbo Feng, Guosheng Dai, Jinsong Jiang, Hui Huang, Qingjun Ji, Minglang Zhou, Dapeng Li, Wei Chai,
https://doi.org/10.18632/aging.205455 pp 1750—1766
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Tremella fuciformis polysaccharides induce ferroptosis in Epstein–Barr virus-associated gastric cancer by inactivating NRF2/HO-1 signaling

Wencheng Kong, Xinchun Liu, Hangzhang Zhu, Sixing Zheng, Guang Yin, Panpan Yu, Yuqiang Shan, Shenglin Ma, Rongchao Ying, Huicheng Jin,
https://doi.org/10.18632/aging.205457 pp 1767—1780
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Identification of key ferroptosis genes and mechanisms associated with breast cancer using bioinformatics, machine learning, and experimental validation

Shuang Liang, Yan-Ming Bai, Bo Zhou,
https://doi.org/10.18632/aging.205459 pp 1781—1795
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Circ0060467 sponges miR-6805 to promote hepatocellular carcinoma progression through regulating AIFM2 and GPX4 expression

Ye-Ru Tan, Bao-Hong Jiang, Wen-Jie Feng, Zhi-Long He, Yi-Ling Jiang, Yi Xun, Xiao-Ping Wu, Yue-Hua Li, Hong-Bo Zhu,
https://doi.org/10.18632/aging.205460 pp 1796—1807
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Identification of BANF1 as a novel prognostic biomarker in gastric cancer and validation via in-vitro and in-vivo experiments

Yuanmin Xu, Xu Wang, Weiwei Yuan, Ling Zhang, Wei Chen, Kongwang Hu,
https://doi.org/10.18632/aging.205461 pp 1808—1828
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IL-17 promotes IL-18 production via the MEK/ERK/miR-4492 axis in osteoarthritis synovial fibroblasts

Kun-Tsan Lee, Chih-Yang Lin, Shan-Chi Liu, Xiu-Yuan He, Chun-Hao Tsai, Chih-Yuan Ko, Yuan-Hsin Tsai, Chia-Chia Chao, Po-Chun Chen, Chih-Hsin Tang,
https://doi.org/10.18632/aging.205462 pp 1829—1844
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Activation of Notch-1 signaling pathway in macrophages to secrete PD-L1 and regulate cytotoxicity of CAR-T cells in diffuse large B-cell lymphoma

Weijing Li, Lili Wu, Chen Huang, Hongqing Ma, Lianjing Wang, Wei Liu, Lihong Liu,
https://doi.org/10.18632/aging.205463 pp 1845—1859
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The integration of multi-omics analysis and machine learning for the identification of prognostic assessment and immunotherapy efficacy through aging-associated genes in lung cancer

Wei Lu, Yun Zhou, Ruixuan Zhao, Qiushi Liu, Wei Yang, Tianyi Zhu,
https://doi.org/10.18632/aging.205464 pp 1860—1878
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CDK16 as a potential prognostic biomarker correlated with an immunosuppressive tumor microenvironment and benefits in enhancing the effectiveness of immunotherapy in human cancers

Juntao Qi, Gujie Wu, Min He, You Xu, Zheng Yang, Liang Ding, Yan Wang, Zhi Zhang,
https://doi.org/10.18632/aging.205465 pp 1879—1896
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Knockdown of RNA-binding protein IMP3 suppresses oral squamous cell carcinoma proliferation by destabilizing E2F5 transcript

Zhenzhen Wang, Huahua Zhang, Fang Li, Chen Huang,
https://doi.org/10.18632/aging.205466 pp 1897—1910
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Investigation of Tongxie-Yaofang formula in treating ulcerative colitis based on network pharmacology via regulating MAPK/AKT signaling pathway

Xinhong Liu, Mao Ye, Yinglin He, Qin Lai, Bo Liu, Leichang Zhang,
https://doi.org/10.18632/aging.205467 pp 1911—1924
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Melatonin improves stroke through MDM2-mediated ubiquitination of ACSL4

Qing Ji, Le Zhang, Hui Ye,
https://doi.org/10.18632/aging.205469 pp 1925—1937
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Long noncoding RNA MEG3 regulates cell proliferation and apoptosis by disrupting microRNA-9-5p-mediated inhibition of NDRG1 in prostate cancer

Zhenpeng Lian, Pei Tian, Shenfei Ma, Taihao Chang, Ranlu Liu, Qingchuan Feng, Jing Li,
https://doi.org/10.18632/aging.205472 pp 1938—1951
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Consistency of mouse models with human intracerebral hemorrhage: core targets and non-coding RNA regulatory axis

Sinan Jin, Jincheng Meng, Chong Zhang, Jiping Qi, He Wu,
https://doi.org/10.18632/aging.205473 pp 1952—1967
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The role of miR-6884-5p in epithelial-mesenchymal transition in non-small cell lung cancer

Lianyong Zhang, Wei Chi, Xue Wang, Jingjing Li, Fei Li, Yuxia Ma, Qianyun Zhang,
https://doi.org/10.18632/aging.205474 pp 1968—1979
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Correction

Correction for: Xuesaitong promotes myocardial angiogenesis in myocardial infarction mice by inhibiting MiR-3158-3p targeting Nur77

Jiangquan Liao, Mingjing Shao, Yan Wang, Peng Yang, Dongliang Fu, Mengru Liu, Tong Gao, Kangkang Wei, Xianlun Li, Jinhang Du,
https://doi.org/10.18632/aging.205576 pp 1980
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Retraction

Retraction: MiR-27a promotes the autophagy and apoptosis of IL-1β treated-articular chondrocytes in osteoarthritis through PI3K/AKT/mTOR signaling

Chen Cai, Shaoxiong Min, Bo Yan, Wen Liu, Xiao Yang, Liuxun Li, Ting Wang, Anmin Jin,
https://doi.org/10.18632/aging.204906 pp 1981—1982
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Volume 16, Issue 2  
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