Retraction Volume 16, Issue 2 pp 1981—1982
Retraction: MiR-27a promotes the autophagy and apoptosis of IL-1β treated-articular chondrocytes in osteoarthritis through PI3K/AKT/mTOR signaling
- 1 Department of Spine Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China
- 2 Department of Spine Surgery, The Third Affliated Hospital of Southern Medical University, Guangzhou, Guangdong, China
- 3 Department of Cell Biology, School of Basic Medical Science, Southern Medical University, Guangzhou, Guangdong, China
Received: March 12, 2023 Accepted: January 13, 2024 Published: January 30, 2024
https://doi.org/10.18632/aging.204906How to Cite
Copyright: © 2024 Cai et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
This article has been retracted: Aging has completed its investigation of this paper. We found that four images of immunofluorescent staining in Figure 5A were previously published as Figure 6A in a 2012 paper by different authors [1]. In addition, Western blot bands in Figure 5B show internal duplication with bands in Figures 7B and Figure 2C in an earlier published paper from Huang et al [2] as well as Figure 6A in an unrelated paper [3]. There are also multiple overlaps between Western blot bands in Figures 6G and 7B with figures in unrelated papers all published in 2019 [4–6]. The authors informed the journal that they cannot reproduce the data published in the paper. As a result, all authors agreed that the article should be retracted.
References
- 1. Kumari S, Mehta SL, Li PA. Glutamate induces mitochondrial dynamic imbalance and autophagy activation: preventive effects of selenium. PLoS One. 2012; 7:e39382. https://doi.org/10.1371/journal.pone.0039382 [PubMed]
- 2. Huang YH, Sun Y, Huang FY, Li YN, Wang CC, Mei WL, Dai HF, Tan GH, Huang C. Toxicarioside O induces protective autophagy in a sirtuin-1-dependent manner in colorectal cancer cells. Oncotarget. 2017; 8:52783–91. https://doi.org/10.18632/oncotarget.17189 [PubMed]
- 3. Huang L, Jian Z, Gao Y, Zhou P, Zhang G, Jiang B, Lv Y. RPN2 promotes metastasis of hepatocellular carcinoma cell and inhibits autophagy via STAT3 and NF-κB pathways. Aging (Albany NY). 2019; 11:6674–90. https://doi.org/10.18632/aging.102167 [PubMed]
- 4. Liang M, Shao A, Tang X, Feng M, Wang J, Qiu Y. MiR-34a affects dexmedetomidine-inhibited chronic inflammatory visceral pain by targeting to HDAC2. BMC Anesthesiol. 2019; 19:131. https://doi.org/10.1186/s12871-019-0801-z [PubMed]
- 5. Li G, Tan W, Fang Y, Wu X, Zhou W, Zhang C, Zhang Y, Liu Y, Jiu G, Liu D. circFADS2 protects LPS-treated chondrocytes from apoptosis acting as an interceptor of miR-498/mTOR cross-talking. Aging (Albany NY). 2019; 11:3348–61. https://doi.org/10.18632/aging.101986 [PubMed]
- 6. Chen T, Zhang Y, Liu Y, Zhu D, Yu J, Li G, Sun Z, Wang W, Jiang H, Hong Z. MiR-27a promotes insulin resistance and mediates glucose metabolism by targeting PPAR-γ-mediated PI3K/AKT signaling. Aging (Albany NY). 2019; 11:7510–24. https://doi.org/10.18632/aging.102263 [PubMed]