Research Paper Volume 16, Issue 2 pp 1879—1896

CDK16 as a potential prognostic biomarker correlated with an immunosuppressive tumor microenvironment and benefits in enhancing the effectiveness of immunotherapy in human cancers


Figure 7. The relationship between CDK16 and the regulation of the tumour microenvironment. (A) Heatmap represents the correlation between CDK16 expression and TME scores in pan-cancer. (B) The relationship between CDK16 and the tumour microenvironment. (C) After H1299 cells were transfected with si-CDK16, the level of CDK16 was evaluated by qRT-PCR. (D) The cell viability of cells was examined by CCK-8 assay. Red represents positive correlation, blue represents negative correlation, and the darker the color, the stronger the correlation. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.