Figure 6. Effects of CPL on TMA/TMAO metabolism in colonic contents. (A) Composition of choline metabolites. (B) Heatmap of choline metabolites. (C) Concentration of choline. (D) Concentration of DTMA. (E) Concentration of TMA. (F) Concentration of TMAO. (G) CPL affected TMA/TMAO metabolism. n = 5 mice per group. The data are presented as the mean ± SEM. Statistical analysis was performed using Student’s t test. *p < 0.05, **p < 0.01. Abbreviations: DTMA: dimer trimethylamine; TMA: trimethylamine; TMAO: trimethylamine N-oxide.