Research Paper Volume 16, Issue 6 pp 5452—5470

Cyclocarya paliurus leaves alleviate high-sucrose diet-induced obesity by improving intestinal metabolic disorders


Figure 8. The levels of eighteen intestinal metabolites and the expression of tight junction proteins were confirmed in the KM experiment. (A) Heatmap of eighteen reconfirmed intestinal metabolites. (B) Concentration of indole derivatives. (C) Concentration of TMA and TMAO. (D) Concentrations of bile acids. (E) Relative gene expression of claudin-1, occludin and ZO-1. (F) Protein expression of claudin-1, occludin and ZO-1. n = 6 mice per group. The data are presented as the mean ± SEM. Statistical analysis was performed using Student’s t test. *p < 0.05, **p < 0.01, Abbreviation: ns: not significant.