Research Paper Volume 16, Issue 7 pp 5905—5915

Cepharanthine maintains integrity of the blood-brain barrier (BBB) in stroke via the VEGF/VEGFR2/ZO-1 signaling pathway


Figure 1. Cepharanthine (CEP) improved neurological dysfunction in a middle cerebral artery occlusion (MCAO) mice model. (A) Molecular structure of Cepharanthine; (B) Neurological score graph of the three experimental groups (**, P<0.01 vs. vehicle group; ##, P<0.01 vs. MCAO group).