Research Paper Volume 16, Issue 7 pp 5905—5915

Cepharanthine maintains integrity of the blood-brain barrier (BBB) in stroke via the VEGF/VEGFR2/ZO-1 signaling pathway


Figure 2. Cepharanthine (CEP) prevented the increase in blood-brain barrier (BBB) permeability in MCAO mice model. Blood-brain barrier permeability was measured by diffusion of sodium fluorescein assay (**, P<0.01 vs. vehicle group; ##, P<0.01 vs. MCAO group).