Research Paper Volume 16, Issue 7 pp 5905—5915

Cepharanthine maintains integrity of the blood-brain barrier (BBB) in stroke via the VEGF/VEGFR2/ZO-1 signaling pathway


Figure 3. Cepharanthine (CEP) restored the expression of ZO-1 in the cortex of MCAO mice model. (A) mRNA of ZO-1; (B) Protein of ZO-1 as measured using immunostaining. Scale bars, 100 μm (**, P<0.01 vs. vehicle group; ##, P<0.01 vs. MCAO group).