Research Paper Volume 16, Issue 6 pp 5751—5771

Comprehensive analysis of scRNA-seq and bulk RNA-seq reveal the characteristics of disulfidptosis and a prognostic signature in BLCA


Figure 4. Establishment of the DRGs risk score and its interaction with tumor clinicopathological characteristics. (A) Cross-validation was performed for tuning parameter selection in the LASSO Cox regression model. (B) LASSO coefficient profiles of the DRGs. (C) Sankey diagram showing the changes of DRG clusters, survival status, gene cluster, and disulfidptosis score. (D) Differences in disulfidptosis score between 2 DRG clusters. P < 0.001). (E) Differences in disulfidptosis score among 2 gene clusters. The Kruskal-Wallis test was used to compare the statistical difference between 2 gene clusters. (F) The difference of DRG expression in low-risk and high-risk group. *P < 0.05, **P < 0.01, ***P < 0.001.