Research Paper Volume 16, Issue 8 pp 6757—6772

USP15 facilitates the progression of bladder cancer by amplifying the activation of the NF-κB signaling pathway


Figure 4. USP15 knockdown suppresses bladder cancer cell proliferation, migration, and invasion in vitro. (A, B) Proliferation capacity of bladder cancer cells J82 treated with sh-NC or sh-USP15 was detected by colony formation assays (***p < 0.001; scale bar, 50 μm). (C, D) Invasion and migration assays were conducted to evaluate the effect of USP15 knockdown on the metastatic ability of bladder cancer cells J82 (Magnification 200X). (*p < 0.05, **p < 0.01, ***p < 0.001).