Research Paper Volume 16, Issue 8 pp 6773—6795

An LRPPRC-HAPSTR1-PSMD14 interaction regulates tumor progression in ovarian cancer


Figure 2. Functional enrichment analysis of HAPSTR1 and its correlated molecules and experimental verification. (A) GO/KEGG analyses of genes positively and negatively correlated with HAPSTR1 in the LinkOmics database. (B) GO/KEGG analysis was used to annotate the results of mass spectrometry (MS). (C, D) Western blotting demonstrated that HAPSTR1 stimulated the EMT pathway and suppressed autophagy. (E) Intersection of data from Immunoprecipitation-Mass Spectrometry (IP-MS), GSE204961, and BIOGRID datasets. *, p < 0.05; **, p < 0.01; ***, p < 0.001.