Research Paper Volume 16, Issue 7 pp 6537—6549

A prognostic signature established based on genes related to tumor microenvironment for patients with hepatocellular carcinoma


Figure 1. Differential expression and NMF consensus clustering analysis of TRGs. (A) Volcano plot shows DE-TRGs among 374 patients with HCC and 50 control samples. (B) NMF consensus clustering for the k = 3. (C) The cophenetic correlation coefficient indicates the stability of the cluster obtained using the NMF algorithm. (D) RSS reflects the performance of the model in clustering. (E) The KM survival curves show the OS and (F) the PFS of patients in the three subtypes. (G) The alluvial map shows the distribution of these subtypes in immune subtypes.