Research Paper Volume 16, Issue 8 pp 6809—6838

Comprehensive analysis of macrophage-related genes in prostate cancer by integrated analysis of single-cell and bulk RNA sequencing


Figure 5. The immune landscape of macrophage-related molecular subtypes. (A) The boxplot displays the difference in immune-related functions between different clusters. (B) Two clusters have different levels of immune cell infiltration. (C) Seven immune infiltration software displays the immune infiltration between different clusters. (D) Comparing the expression of HLA molecules between two clusters. (E) Expression of immune checkpoint molecules between the two clusters. (F) The comparisons of stromal score, immune score, and estimate score between clusters. Comparing immunophenoscores (IPS) across clusters; (G) CTLA4−_PD1−, (H) CTLA4−_PD1+, (I) CTLA4+_PD1−, and (J) CTLA4+_PD1+. ns, not significant; **P < 0.01; ***P < 0.001.