Research Paper Volume 16, Issue 8 pp 6852—6867

ITGAM is a critical gene in ischemic stroke


Figure 5. Hub gene analysis. (A) Construction of PPI network for DEGs through STRING database. (B) The PPI network was optimized by Cytoscape software. (C) Ten hub genes were filtered out per the degree method utilizing the Cytoscape’s cytoHubba plugin. (D) Enrichment analysis of 10 hub genes was performed by Metascape database. Abbreviations: PPI, protein-protein interaction; DEGs, differentially expressed genes.