Research Paper Volume 16, Issue 8 pp 6868—6882

lincRNA00907 promotes NASH progression by targeting miRNA-942-5p/TAOK1


Figure 6. TAOK1 identified as a downstream target of miR-942-5p. (A) miRDB, TarBase, and TargetScan databases were used to predict the downstream target genes of miR-942-5p; (B) overexpression of miR-942-5p downregulated the mRNA levels of TAOK1; (C) following knockdown of miR-942-5p, an elevation in the mRNA levels of TAOK1 was observed; (D) the predicted specific binding sequence between miR-942-5p and TAOK1; (E) a dual-luciferase assay confirmed the binding of miR-942-5p and TAOK1.