Research Paper Volume 16, Issue 8 pp 6898—6920

Tertiary lymphoid structures associated with enhanced anti-tumor immunity and favorable prognosis in cervical squamous carcinoma


Figure 1. Integrated scRNA-seq analysis of tumor tissues from CESC patients. (A) t-SNE visualization of 20,117 single cells passed quality controls, colored by three CESC patients. (B) Unsupervised clustering of 20,117 cells. (C) t-SNE visualization of major cell types. (D) Violin plot showing the expression levels of conventional gene signatures. (E) Heatmap for gene expression levels of top ten cell-type-specific genes. (F) Bar plot showing the cellular components of each CESC patients. (G) Heatmap showing the expression of nine TLS signatures of the five major cell types.