Research Paper Volume 16, Issue 8 pp 6990—7008

Activating transcription factor 6 alleviates secondary brain injury by increasing cystathionine γ-lyase expression in a rat model of intracerebral hemorrhage


Figure 5. Up-regulation of ATF6 reduced apoptosis and neuron loss induced by ICH. (A, B) Apoptotic cells were labeled in brain sections using TUNEL staining, and the percentage of apoptotic cells was analyzed statistically. Arrow indicated TUNEL positive cells. Nuclei were labeled with DAPI (blue). (C, D) FJC staining. Arrow indicated FJC positive cells. (E) ROS. (F) LDH. (G) MAD. (H) Even blue extravasation. (I) XO Level. (J) GSH level. Scale bar = 50 um. The black dots represent individual data in each group. **p < 0.01 and *p < 0.05, @@p < 0.01 and @p < 0.05, ##p < 0.01 and #p < 0.05, n = 6.