Research Paper Volume 16, Issue 8 pp 7043—7059

Identification of biomarkers and immune infiltration characterization of lipid metabolism-associated genes in osteoarthritis based on machine learning algorithms


Figure 4. Feature biomarkers selection via machine language algorithms. (A) Key LAGs screening by LASSO analysis. (B) RF analysis of key DE-LAGs, the filter condition for screening feature variates was set at: importance > 3. (C) SVM-RFE algorithm for selecting the feature DE-LAGs. (D) Venn network plot showed the three diagnostic feature biomarkers based on LASSO, SVM-RF and RF algorithm.