Research Paper Volume 16, Issue 7 pp 5811—5828

The impact of continuous and intermittent ketogenic diets on cognitive behavior, motor function, and blood lipids in TgF344-AD rats


Figure 3. Plasma level of amyloid beta (Aβ) and phosphorylated Tau 181 (pTau). (A) Mean circulating Aβ40, (B) Aβ42, (C) Aβ42/42 ratio, (D) pTau, and (E) total Tau were measured in male and female rats fed control diet (CD), intermittent ketogenic diet (IKD) or ketogenic diet (KD) (n = 6–8/group). Aβ40, Aβ42, and Aβ42/40 ratio data were analyzed by repeated measures two-way ANOVA with Tukey’s post-hoc pairwise comparisons. Phosphorylated and total Tau data were analyzed using Kruskal-Wallis’s test with Dunn’s post-hoc to compare differences between diet groups within sex. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 indicate significant differences between groups.