Research Paper Volume 16, Issue 8 pp 6631—6651

A novel deep proteomic approach in human skeletal muscle unveils distinct molecular signatures affected by aging and resistance training


Figure 2. Additional protein classifications. Legend: Each fraction was found to contain nuclear proteins that regulate chromatin structure and gene expression (A), mitochondrial proteins related to oxidative phosphorylation and mitochondrial protein synthesis (B), proteolysis-related proteins (C), proteins localized to the sarcolemma and solute carrier proteins (D), exercise-relevant phosphosignaling proteins (E), and proteins associated with protein synthesis (F). Abbreviations: Mito., mitochondrial; Ub, ubiquitin; MAPKs, mitogen of activated protein kinases; mTORC1, mechanistic target of rapamycin complex 1; AMPK, AMP-activated protein kinase; CAMK, Ca2+/calmodulin-dependent protein kinase; Euk., eukaryotic.