Research Paper Volume 16, Issue 8 pp 7188—7216

Integrative analysis based on the cell cycle-related genes identifies TPX2 as a novel prognostic biomarker associated with tumor immunity in breast cancer


Figure 2. Identification of DEGs from 3 GEO datasets and TCGA dataset of breast cancer (BRCA) and GO enrichment analysis of consistent DEGs of the datasets. (A) Volcano maps of genes detected in BRCA datasets. Red and blue represent up- and downregulated genes, respectively. (B) Venn diagram showing overlapped part of DEGs in four BRCA datasets. (C) GO enrichment analysis of the overlapped part of the DEGs. (D) Circle enrich plot. GO enrichment analysis for 34 DEGs, terms with p < 0.05 was believed to be enriched significantly. (E) The association of these 18 candidate genes in breast cancer, *P < 0.05, **P < 0.01.