Research Paper Volume 16, Issue 8 pp 7277—7292

Medium-chain chlorinated paraffins (MCCPs) induce renal cell aging and ferroptosis


Figure 3. Effects of MCCPs on renal cell senescence. (A) Sa-β-gal staining of NRK-52E and HEK293 cells after MCCPs treatment. (B) Effects of MCCPs on p16/p21/p53 expression in NRK-52E and HEK293 cell model. (C) Effect of MCCPs on the expression of CyclinD1, CyclinE1 and γ-H2AX. p < 0.05 indicates significant difference.