Research Paper Volume 16, Issue 8 pp 7331—7356

Integrated multi-omics analysis and machine learning identify hub genes and potential mechanisms of resistance to immunotherapy in gastric cancer


Figure 2. Selection of hub genes from prognostic genes. (A) Shadow feature plot for Boruta algorithm. (B) Confirmed plot for Boruta algorithm. (C) XGBoost analysis. (D) Venn diagram of hub genes identification using different methods. (EG) Kaplan-Meier survival analysis of EGFLAM, RASGRF2, and CDH6 (p<0.001, p=0.008, and p<0.001, respectively).