Research Paper Volume 16, Issue 8 pp 7331—7356

Integrated multi-omics analysis and machine learning identify hub genes and potential mechanisms of resistance to immunotherapy in gastric cancer


Figure 5. Multiple methods for identifying CAFs-associated genes related to hub genes. (A) Pearson correlation analysis of hub genes with immunotherapy-related indicators. (B) The Kaplan-Meier survival analysis of CAFs scores was calculated using three methods (p=0.006, p=0.006, and p=0.004, respectively). (C) Scale independence and mean connectivity analysis. (D) Cluster dendrogram among modules. (E) Scatterplot of MM and GS from the black module. (F) Module-trait relationships. *p < 0.05, **p < 0.01, ***p < 0.001.